Ultrasound in Rheumatoid Arthritis: Assessment of Synovitis Using the EULAR-OMERACT Scale (0–3) and Power Doppler
Principles of Synovitis Assessment
When scanning the joints of the hand and wrist, longitudinal and transverse planes from anatomical landmarks are used. Joint distension, hypo-/hyperechoic synovial proliferation, and joint effusion deeper than the echogenic capsule are assessed (Griffith, 2025). To differentiate fluid from synovitis, color Doppler and, to a lesser extent, probe compression are used.
Grayscale Mode and EULAR-OMERACT Grades
The standardized consensus system for synovitis assessment was developed by the EULAR-OMERACT ultrasound working group; its reliability and applicability to multiple joints have been confirmed (Terslev L, Naredo E, Aegerter P et al. RMD Open 2017; 3: e000427). The relevance of grade 1 grayscale findings in wrists and small joints for assessing subclinical synovitis in RA is discussed in the literature (Witt M et al., 2013).
The significance of the assessment zone is noted: palmar compared to dorsal assessment of synovitis in RA (Vlad V et al., BMC Musculoskelet Disord 2011).
Power Doppler
To assess hyperemia, it is necessary to optimize device settings, use minimal probe pressure, and record the degree as mild, moderate, or severe (Griffith, 2025). The settings of power and color Doppler directly affect the scoring of disease activity in patients with RA (Torp-Pedersen S et al., Arthritis Rheumatol 2015;67(2):386–395).
Power Doppler is used for quantitative assessment of hand synovitis in RA, including monitoring response to anti-TNF-α therapy (Ribbens C et al., Radiology 2003;229(2):562–569). In very early inflammatory arthritis, adding power Doppler to standard assessment methods increases diagnostic value (Freeston JE et al., Ann Rheum Dis 2010), and erosions and power Doppler signal have prognostic significance regarding radiographic damage (Funck-Brentano T et al., 2013).
Tenosynovitis
In addition to synovitis, tenosynovitis is assessed; a semi-quantitative OMERACT system, sensitive to changes, has been validated for it (Ammitzboll-Danielsen M et al., Rheumatology 2016). A significant feature is the peritendinous hypoechoic rim on power Doppler (Breidahl WH et al., J Ultrasound Med 1998).
Frequently asked questions
What scale is used for standardized synovitis assessment?
The EULAR-OMERACT consensus system by the ultrasound working group; its reliability and applicability to multiple joints have been confirmed (Terslev L et al., RMD Open 2017).
How to differentiate effusion from synovitis?
Color Doppler and, to a lesser extent, probe compression help; synovial proliferation appears as hypo-/hyperechoic tissue deeper than the echogenic capsule (Griffith, 2025).
How to properly assess hyperemia with power Doppler?
Optimize device settings, use minimal probe pressure, and record the degree as mild, moderate, or severe. Doppler settings directly affect the scoring (Torp-Pedersen S et al., 2015).
Is there significance to grade 1 grayscale findings?
The relevance of grade 1 grayscale findings in wrists and small joints for assessing subclinical synovitis in RA is considered in the literature (Witt M et al., 2013).
Does power Doppler have prognostic value?
Yes: erosions and power Doppler signal have prognostic significance regarding radiographic damage in early arthritis (Funck-Brentano T et al., 2013).